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Predictive value of a proteomic signature in patients with non-small-cell lung cancer treated with second-line erlotinib or chemotherapy (PROSE): a biomarker-stratified, randomised phase 3 trial.

Oncologists should be able to readily glean the information needed to select appropriate therapy, and to explain the result to their patients.

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Small-Cell Lung Cancer Treated with EGFR Tyrosine Kinase Inhibitors.

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In the Phase III program, the major side effects were flushing, Corporategastrointestinal disorders, headache and nasopharyngitis.

For time to progression on TKI, distribution plots were compared with Wilcoxon rank tests.

Moos R, Thuerlimann BJ, Aapro M, et al: Pegylated liposomal doxorubicin-associated hand-foot syndrome: Recommendations of an international panel of experts.

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In other words, patients that expressed a large amount of epidermal growth factor receptor had better results with erlotinib than those patients with lower amounts of the receptor protein.

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Gefitinib was supplied by Polymed Therapeutics, Inc.

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